INPUT PAPER: Clusters meet Regions event in Foligno Clusters as Drivers of the Green and Digital Transition in Regional Innovation Ecosystems

The following paper presents observations on the cluster landscape and innovation ecosystem of the Italian region of Umbria, to inform strategic reflections during the Clusters Meet Regions event in Foligno on June 24 & 25, 2025. It outlines key characteristics of the region’s economic profile, innovation performance, and specialisation patterns, and highlights the role that clusters play in supporting regional development. In line with the focus of the event — “Clusters as Drivers of the Green and Digital Transition in Regional Innovation Ecosystems” — the paper explores how cluster organisations contribute to regional industrial transformation, resilience, and competitiveness. By analysing existing cooperation structures and Smart Specialisation priorities, the paper identifies areas of strength and potential directions for future policy development, particularly in the areas of decarbonisation, digitalisation, skills development and interregional cooperation. The insights aim to support discussions among policymakers, cluster managers, SMEs, and other regional stakeholders at the event.